Vaccines and immunity and nervous system. Explained links...

After a complex research on previous studies and lots of reading of scientific papers, here it is, the focus of this ‘recent research of research’ of mine:

Impact of vaccines on immunity (or body defense system) and the nervous system. 

This story will come in chapters, it's long BUT it is very interesting. I was quite shocked to find SO many studies published in peer review journals confirming the link between vaccines and disesases...both in adults and in children.

What is the relationship between an increasing number of vaccinations and the appearance of several otherwise unexplained diseases of our times, like: 1. autoimmune or autoinflammatory diseases such as Systemic Lupus Erythematosus, Multiple Sclerosis, or 2. neurodegenerative diseases, like Alzheimer’s Disease (AD), or 3. behavioral-emotional diseases like Autism? 
All such syndromes or diseases have been increasing in the past 2 generations, however this observation is difficult to measure in an absolute manner since diagnosis has also improved – but not only: for example, neurodegenerative diseases: a study estimated that in 2006, 0.40% of the world population (26.6 million) were affected by AD, and that this rate would triple by 2050; behavioral diseases, 6.7 in 1000 children had autism in 2000 and 14.7 in 1000 children in 2010; autoimmune diseases: altogether … 1 in 20 people in Western countries have an autoimmune disease!

When I came to learn about the tight connection between nervous and immune system in both development and functioning, many things became clear or plausible. The immune system develops – and later works - tightly with the nervous system. The two interact extensively via cytokines, messenger molecules produced by cells of the immune system, and neuropeptides, messengers produced by the nervous systems: cytokines are recognized by nervous system glial cells, and neuropeptides are recognized by immune cells. Some cytokines not only control the development of the nervous system but also help in its protection and regeneration. There is a constant talk between the two systems.
 
The immune system pervades our organism by interacting with the nervous system and endocrine system, and checking everywhere for the presence of invaders or dead or malfunctioning cells to be eliminated. It permeates every component of our body with its cells and messengers.

The immune system is our protector from harmful stimuli, like pathogens, damaged cells, irritants, etc. Inflammation is the number one response of the immune system to fight any attack from inside or outside. Examples of inflammation are: a bruise from a fall or an infection, which are characterized by redness, warmth, pain, swelling.  

Autoimmune and autoinflammatory reactions and diseases are the results of an improper functioning of the immune system, in which the immune cells mistakenly fight against their own organism. The body attacks and destroys itself. Such is the case of multiple sclerosis (MS), in which the myelin sheath of neurons is destroyed, or of systemic Lupus Erythematosus (SLE), in which skin, joints, kidneys and brain get attacked.

Neurodegenerative diseases, like AD, Parkinson’s and ALS (Amyotyroiphic lateral sclerosis or motoneuron disease), are caused by loss of structure and function of the nervous system. There are commonalities among them, like strange conglomerates of proteins and nervous cells death.

Behavioral-emotional diseases affect behavior and emotion: included are ADHD, schizophrenia, bipolar, and sometimes AD.

All such diseases, like all diseases in general, have a genetic AND an environmental component. Your chances to get one of these (or any other) disease depends on your DNA make-up as well as on the external conditions: life style, where you live, diet, what you do, your exposure to toxins, amount and type of physical exercise etc. Which means that, IF you have the genes for a disease, you do not NECESSARILY get it, if you avoid certain environmental triggers.

What is the common factor between autoimmune or autoinflammatory diseases, neurodegenerative diseases and behavioral diseases? There is a theory and many proven correlations that adjuvants used in medicine (vaccination, implants) could cause these conditions.

Adjuvants are pharmacological agents that modify the effect of another agent. Immunologic adjuvants are substances that are used in the delivery of a vaccine to make it more long-lasting and effective. Such adjuvants interact with cells in the immune system to make it more reactive in the defense towards antigens = toxic molecules or organisms (ex. bacteria or viruses that are delivered through the vaccine to prepare the system of defense in face of a real invasion). Adjuvants also provide antigen transport to the lymph nodes, where cells of the immune systems can be produced in high number to fight specifically that antigen; thus such adjuvants provide a longer exposure of pathogens to the immune system and a more robust response. In doing so, they enable the decrease of the amount of antigen needed and thereby the production of a larger number of vaccines (!). The most common immunological adjuvant is alum or hydrated potassium aluminium sulfate, used in vaccines since 1927. Silicon is also considered an adjuvant when used in breast implants.

Adjuvants and autoimmune diseases? Formerly, adjuvants were thought to be harmless, but studies of animal models and human reactions to vaccines demonstrated the ability of some of them to cause autoimmunity and autoimmune diseases in some patients.
 
Vaccines are important achievements of modern medicine and are commonly and safely inoculated to human and animals worldwide. However, sometimes, vaccines can induce the appearances of autoantibodies, inflammatory conditions and autoimmune diseases: arthritis, neuronal damage, fatigue, encephalitis and vasculitis have been frequently described in association to vaccines. A similar association has been proven between silicon in implants and other autoimmune reactions. The factors with the adjuvant activity (infectious agents and alum in vaccines and silicon in breast implants) are the link to the immune-mediated diseases. Such association has been observed in both in animals (where tests could be run and causation proven) and in humans.

Causation versus correlation: Such association between vaccines, or other environmental factors, with immune-mediated diseases have been shown in numerous studies, however it is almost impossible to prove a cause-and-effect relationship. They just happen to appear in conjunction.

However, in some (many!) cases this causation has been scientifically proven and in few cases the causation is now accepted by the medical community and the decision makers: in 1976 an outbreak of Guillain-Barré syndrome (a dysfunction of the peripheral nervous system causing paralysis and eventually death) followed vaccination with the “swine flu” vaccine. After complete acceptance of this causation link, warnings of possible side effects as GB syndrome are still notified on labels in present flu-vaccines packages. Similar causal relationship (i.e. the vaccine caused the disease) have been accepted for:

Oral Polio Vaccine: transverse myelitis (inflammation of the spinal cord and sensory and motor loss and paralysis), inflammatory myopathies
Diphtheria-tetanus-pertussis Vaccine (DTP): arthritis, inflammatory myopathies
Diphtheria with scarlet fever vaccine: inflammatory myopathies
Pertussis Vaccine: allergic disorders (asthma, hay fever, food allergy),
Smallpox Vaccine: inflammatory myopathies,
Measles-mumps-rubella Vaccine (MMR): arthritis, autoimmune thrombocytopenia
Tuberculosis bacillus Calmette-Guérin Vaccine: inflammatory myopathies
Tetanus Vaccine:  inflammatory myopathies
Human Papilloma virus Vaccine: SLE
Hepstein Barr Vaccine: SLE
Hepatitis B Vaccine: arthritis, Rheumatoid Arthritis, SLE, inflammatory myopathies
Influenza vaccine: polymyalgia rheumatic, SLE, Rheumatoid arthritis
H1N1 Vaccine: inflammatory myopathies, sometimes associated with interstitial lung disease

The list goes on. The more I search the more I find scientific published research on the relations between vaccines an autoimmune diseases. There are probably as many works stating the opposite. But here you go, up to you to juice out a truth. If there is a risk….why running it? Especially, why taking it for your child?
 
…next on breast implants and auto-immune diseases, ASIA syndrome, autism, children vaccination....




This text is to be taken as information, always refer to your medical doctor for questions. Learn to be informed before conseting on your or your child's health.